Searchable abstracts of presentations at key conferences in endocrinology

ea0063p149 | Diabetes, Obesity and Metabolism 1 | ECE2019

Negative regulation of AMPK-related kinase MPK38/MELK activity by protein phosphatase 5 (PP5)

Seong Hyun A , Ha Hyunjung

Murine protein serine-threonine kinase 38 (MPK38), also known as maternal embryonic leucine zipper kinase (Melk), is a member of the AMP-activated protein kinase (AMPK)-related kinase family and regulates multiple cellular processes, including cell cycle, stem cell self-renewal, apoptosis, carcinogenesis, and metabolism, and is activated in response to apoptosis signal-regulating kinase 1 (ASK1)/TGF-β/p53 signals. A serine/threonine protein phosphatase PP5 has been sugges...